ZNF746
Identifiers
AliasesZNF746, P.A.R.I.S, PARIS, zinc finger protein 746
External IDsOMIM: 613914 MGI: 1916478 HomoloGene: 19783 GeneCards: ZNF746
Orthologs
SpeciesHumanMouse
Entrez

155061

69228

Ensembl

ENSG00000181220

ENSMUSG00000057691

UniProt

Q6NUN9

Q3U133

RefSeq (mRNA)

NM_001163474
NM_152557
NM_001363517
NM_001394198

NM_001163475
NM_001347142
NM_001362062

RefSeq (protein)

NP_001156946
NP_689770
NP_001350446

NP_001156947
NP_001334071
NP_001348991

Location (UCSC)Chr 7: 149.47 – 149.5 MbChr 6: 48.04 – 48.06 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Zinc finger protein 746 also known as Parkin-interacting substrate (PARIS) is a zinc finger protein that, in humans, is encoded by the ZNF746 gene and is involved in the neurodegeneration of Parkinson's disease.[5][6]


References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000181220 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000057691 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ↑ Shin JH, Ko HS, Kang H, Lee Y, Lee YI, Pletinkova O, et al. (March 2011). "PARIS (ZNF746) repression of PGC-1α contributes to neurodegeneration in Parkinson's disease". Cell. 144 (5): 689–702. doi:10.1016/j.cell.2011.02.010. PMC 3063894. PMID 21376232.
  6. ↑ "Entrez Gene: ZNF746 zinc finger protein 746 [ Homo sapiens (human) ]".


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