CD14

Molécula CD14
	Renderização baseada em PDB 1WWL.
Estruturas disponíveis
PDB	Busca de ortólogos: PDBe, RCSB
Lista de códigos PDB
	4GLP
Identificadores
Símbolo	CD14
IDs externos	OMIM: 158120 MGI: 88318 HomoloGene: 493 GeneCards: CD14 Gene
Ontologia do gene
Função molecular	•lipopolysaccharide binding; •opsonin receptor activity; •peptidoglycan receptor activity; •lipoteichoic acid binding;
Componente celular	•extracellular region; •extracellular space; •plasma membrane; •cell surface; •endosome membrane; •anchored to membrane; •membrane raft;
Processo biológico	•toll-like receptor signaling pathway; •MyD88-dependent toll-like receptor signaling pathway; •MyD88-independent toll-like receptor signaling pathway; •phagocytosis; •apoptotic process; •inflammatory response; •cell surface receptor signaling pathway; •I-kappaB kinase/NF-kappaB cascade; •response to heat; •positive regulation of tumor necrosis factor production; •toll-like receptor 2 signaling pathway; •toll-like receptor 3 signaling pathway; •toll-like receptor 4 signaling pathway; •TRIF-dependent toll-like receptor signaling pathway; •toll-like receptor TLR1:TLR2 signaling pathway; •toll-like receptor TLR6:TLR2 signaling pathway; •innate immune response; •positive regulation of endocytosis; •positive regulation of cytokine secretion; •cellular response to lipopolysaccharide; •cellular response to lipoteichoic acid;
	Sources: Amigo / QuickGO
Padrões de expressão do ARN
	Mais dados de expressão
Ortólogos

CD14 (cluster of differentiation 14) é um gene humano.[1][2] A proteína codificada por este gene é um componente do sistema imune inato.[3]

editar

Referências

Setoguchi M, Nasu N, Yoshida S, Higuchi Y, Akizuki S, Yamamoto S (Julho de 1989). «Mouse and human CD14 (myeloid cell-specific leucine-rich glycoprotein) primary structure deduced from cDNA clones». Biochim. Biophys. Acta. 1008 (2): 213–22. PMID 2472171. doi:10.1016/0167-4781(80)90012-3
Simmons DL, Tan S, Tenen DG, Nicholson-Weller A, Seed B (1 de janeiro de 1989). «Monocyte antigen CD14 is a phospholipid anchored membrane protein». Blood. 73 (1): 284–9. PMID 2462937
Kirkland TN, Viriyakosol S (1998). «Structure-function analysis of soluble and membrane-bound CD14». Prog. Clin. Biol. Res. 397: 79–87. PMID 9575549

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.

[pmid2472171-1] Setoguchi M, Nasu N, Yoshida S, Higuchi Y, Akizuki S, Yamamoto S (Julho de 1989). «Mouse and human CD14 (myeloid cell-specific leucine-rich glycoprotein) primary structure deduced from cDNA clones». Biochim. Biophys. Acta. 1008 (2): 213–22. PMID 2472171. doi:10.1016/0167-4781(80)90012-3

[pmid2462937-2] Simmons DL, Tan S, Tenen DG, Nicholson-Weller A, Seed B (1 de janeiro de 1989). «Monocyte antigen CD14 is a phospholipid anchored membrane protein». Blood. 73 (1): 284–9. PMID 2462937

[pmid9575549-3] Kirkland TN, Viriyakosol S (1998). «Structure-function analysis of soluble and membrane-bound CD14». Prog. Clin. Biol. Res. 397: 79–87. PMID 9575549