Triazol

Triazol (Htrz) refere-se a qualquer um dos pares de compostos químicos isoméricos com fórmula molecular C2H3N3, com um anel de cinco membros de dois átomos de carbono e três átomos de nitrogênio.

Estrutura

Os dois isômeros são:

  • 1,2,3-Triazole
  • 1,2,4-Triazole
  • 1H-1,2,3-Triazole
    1H-1,2,3-Triazole
  • 2H-1,2,3-Triazole
    2H-1,2,3-Triazole
  • 1H-1,2,4-Triazole
    1H-1,2,4-Triazole
  • 4H-1,2,4-Triazole
    4H-1,2,4-Triazole

Derivados

As drogas antifúngicas triazólicas incluem o fluconazol, isavuconazol, itraconazol, voriconazol, pramiconazol, ravuconazol, terconazol e posaconazol.[1][2]

Referências
  1. Sharma, V.; Bhatia, R. (2011). «Triazoles in Antifungal Therapy: A Review». International Journal of Research in Pharmaceutical and Biomedical. 2 (2): 417-427
  2. Lass-Flörl, C. (2011). «Triazole antifungal agents in invasive fungal infections: a comparative review». Drugs. 71 (18): 2405-2419. doi:10.2165/11596540-000000000-00000
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