Cromossoma 10
Genes
- ALOX5: Arachidonate 5-Lipoxygenase (processes essential fatty acids to leukotrienes, which are important agents in the inflammatory response; also facilitates development and maintenance of cancer stem cells, slow-dividing cells thought to give rise to a variety of cancers, including leukemia);
| Gene | Descrição |
|---|---|
| CDH23 | cadherin-like 23 |
| CXCL12 | chemokine (C-X-C motif) ligand 12, SDF-1, scyb12 |
| EGR2 | early growth response 2 (Krox-20 homolog, Drosophila) |
| ERCC6 | excision repair cross-complementing rodent repair deficiency, complementation group 6 |
| FGFR2 | fibroblast growth factor receptor 2 (bacteria-expressed kinase, keratinocyte growth factor receptor, craniofacial dysostosis 1, Crouzon syndrome, Pfeiffer syndrome, Jackson-Weiss syndrome) |
| HELLS | Lymphoid-specific helicase |
| PCBD1 | 6-pyruvoyl-tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) |
| PCDH15 | protocadherin 15 |
| PTEN gene | phosphatase and tensin homolog (mutated in multiple advanced cancers 1) |
| RET | ret proto-oncogene (multiple endocrine neoplasia and medullary thyroid carcinoma 1, Hirschsprung disease) |
| UROS | uroporphyrinogen III synthase (congenital erythropoietic porphyria) |
Doenças
O cromossomos é constituído por 24 genes colaterais
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